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New York Mets ace Jacob deGrom left his start Wednesday night with right shoulder soreness after three perfect innings, yet another injury scare for the two-time NL Cy Young Award winner amid a historic start to this season.

One start after being pulled from a gem against San Diego with right flexor tendinitis, deGrom went directly down the clubhouse tunnel after finishing the third against the Chicago Cubs. He struck out eight of his nine batters, including his final seven.

DeGrom apeared to grimace after a third-inning pitch to Eric Sogard. He threw 51 pitches, the last a 99 mph fastball to strike out pitcher Robert Stock.

The right-hander lowered his ERA to 0.54, the best ever by a pitcher through 11 starts.

DeGrom pitched one-hit ball over six scoreless innings against the Padres on Friday night before leaving with the flexor issue. He had an MRI the next day that revealed no damage, and he resumed his usual between-start routine. He started Wednesday on his standard four days of rest.

Cincinnati 2, Milwaukee 1: Tyler Mahle tied his career high with 12 strikeouts, Tucker Barnhart drove in the go-ahead run with a double in the seventh inning, and the Cincinnati Reds beat the Milwaukee Brewers 2-1 to finish a three-game sweep.

Cincinnati has won six straight and 11 of 13. The Brewers dropped three straight for the first time in nearly a month and were swept for the third time this season. Milwaukee totaled nine hits and four runs in the series against the Reds.

Mahle (7-2) allowed three hits and a pair of walks over six innings as he surpassed the 10-strikeout mark for the first time this season and fifth of his career. Brad Brach, Sean Doolittle and Lucas Sims completed the five-hitter, with Sims getting the last four outs for his seventh save.

St. Louis 1, Miami 0: Yadier Molina grounded an RBI single down the third base line in the ninth inning and the St. Louis Cardinals edged the Miami Marlins 1-0 to sweep the season series.

Molina’s eighth career regular season walk-off hit came with one out and sent Miami to its fourth straight loss

Colorado 8, San Diego 7: Pinch-hitter Charlie Blackmon singled home the winning run in the ninth inning and the Colorado Rockies shook off a monster homer by Fernando Tatis Jr. to beat the stumbling San Diego Padres, 8-7.

Tatis hit a 477-foot homer, the longest of his career and his NL-leading 21st. He also doubled, but the Padres lost for the 13th time in 17 games.

The gametime temperature was 99 degrees at Coors Field, and the hot weather contributed to a big offensive day. The teams combined for five home runs and 23 hits and neither starter made it out of the fourth inning.

American League

Oakland 8, L.A. Angels 4: Ramón Laureano hit a home run and made a homer-robbing catch in his return from the injured list, and the Oakland Athletics rallied past the Los Angeles Angels 8-4 Wednesday for their sixth straight win.

Shohei Ohtani homered for the second straight day, giving him 19 for the Angels. He also neatly bunted against the shift for a single and stole his team-leading 10th base, a day before he was scheduled to start on the mound.

Chicago White Sox 8, Tampa Bay 7: Yasmani Grandal hit a game-ending RBI single in the 10th inning and the Chicago White Sox beat Tampa Bay 8-7, taking two of three from the Rays in a matchup of division leaders.

Jóse Abreu hit his 12th homer of the season for the White Sox, who’ve won 10 of 13.

Yandy Díaz and Mike Zunino homered for the Rays, who won Monday night’s opener but dropped the next two.

Detroit 6, Kansas City 5: Willi Castro homered during a three-run rally in the seventh inning and the Detroit Tigers beat the Kansas City Royals 6-5 for a three-game sweep.

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